Journal article
The mitochondrial genome of Aelurostrongylus abstrusus-diagnostic, epidemiological and systematic implications
A Jabbar, AR Jex, N Mohandas, RS Hall, DTJ Littlewood, RB Gasser
Gene | Published : 2013
Abstract
Aelurostrongylus abstrusus (Railliet, 1898) is a metastrongylid nematode of major clinical relevance in felids, causing aelurostrongylosis. In spite of its clinical importance in cats, the genetics, epidemiology and biology of this parasite are not entirely understood. mt DNA can provide markers for studies of these areas, but genetic data are scant for A. abstrusus and related lungworms. Here, the mt genome was amplified by long-range polymerase chain reaction (long-PCR) from a single male adult of A. abstrusus, sequenced using 454 technology and annotated using an established bioinformatic pipeline. This circular mt genome is 13,913. bp and contains two ribosomal RNA, 12 protein-coding and..
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Awarded by Biotechnology and Biological Sciences Research Council
Funding Acknowledgements
The Early Career Researcher and Collaborative Research grants (A.J.) from The University of Melbourne are gratefully acknowledged. The present study was supported by ARC grant LP100100091 (R.B.G., A.R.J. and D.T.J.L.). Associated research is also funded by the Australian Research Council (ARC), the National Health and Medical Research Council (NHMRC) and Melbourne Water Corporation.